BIOCHEMICAL CHANGES INDUCED BY HERBICIDE SENCOR IN ALBINO RAT Rattus norvegicus - ALKALINE PHOSPHATASE AND TRANSAMINASES CHANGES IN PLASMA (LIVER FUNCTION)

El-Mahrouky,, Fatma S.; Khidr, Fatma K.; Abou Hashem, A. A. M.; Keshta, T. M. S.

doi:10.21608/jppp.2009.217510

BIOCHEMICAL CHANGES INDUCED BY HERBICIDE SENCOR IN ALBINO RAT Rattus norvegicus - ALKALINE PHOSPHATASE AND TRANSAMINASES CHANGES IN PLASMA (LIVER FUNCTION)

Document Type : Original Article

Authors

Plant Protection Research Institute.

10.21608/jppp.2009.217510

Abstract

Data showed non significant increases in ALT and AST activities throughout the tested periods when rats treated with 1/4 and 1/2 LD₅₀.Sencore herbicide .except at 5th week of the test , 1/2 LD₅₀ induced a significant increases in ALT and AST activities .Regarding to the ALP activity ,1/4 LD₅₀ induced a non significant decreases at 1^st ,2^nd and 4^th week while at 3^rd and 5^th week showed a non significant increases at the same time 1/2 LD₅₀ induced a non significant increases except at 2nd week, there was non significant reduction in plasma ALP activity. Regarding to the bilirubin level ,1/4 and 1/2 LD₅₀ induced a non significant increases for all the tested periods except at 2^nd week with 1/2 LD₅₀exhibited a significant increases in total bilirubin.