EFFICIENCY OF WARFARIN AGAINST CERTAIN ALBINO RODENTS UNDER LABORATORY CONDITIONS

Some toxicity studies of warfarin (0.02% hydroxy coumarin) were carried
against the albino norway rat, Rattus norvegicus and house mouse Mus muscufus.
The gained results were concluded as follows:
A—The Norway rat Hatters norvegricus:
The warfarin bait consumption for each non choice and choice feeding test
was 8.? gr and 4.5 gr for one day. The albino norway rat males were more palatabil
(319%) to warfarin bait than females (31.9%). Warfarin gave 83.3% and 50%
mortality for non choice and choice test. The average time to death was nearly equal
for the obliged and free feeding test which was 5.7 day and 6 days for the albino
norway rat. The reduction of rat body weight who objected to the warfarin bait was —
5.43 gm and 0.7 gm.
For both tests non choice and choice feeding respectively:
B-The house mouse Mus muscufus
The house mouse males and females consumed 2.6 and 2.5
gmi'dayfrndividual and 1.8 and 1.9 gm/day'tindividual for warfarin bait under non choice
and choice feeding system respectively. The palatabitity of house mouse was 45.1%.
The warfarin bait gave 83.4% and 50% for non choice and choice feeding test. The
results cleared that the body weight reduction it was ~2.6 gr and “2.5 gr. for both non
choice and choice feeding system. The general average of time to death in both
obliged and free tests were respectively 1.7 and 8.0 days.