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Khidr, F. (2002). HISTOPATHOLOGICAL CHANGES IN HEART AND LUNG OF ALBINO RAT TREATED WITH MACHETE HERBICIDE. Journal of Plant Protection and Pathology, 27(10), 7043-7052. doi: 10.21608/jppp.2002.255354
Fatma K. Khidr. "HISTOPATHOLOGICAL CHANGES IN HEART AND LUNG OF ALBINO RAT TREATED WITH MACHETE HERBICIDE". Journal of Plant Protection and Pathology, 27, 10, 2002, 7043-7052. doi: 10.21608/jppp.2002.255354
Khidr, F. (2002). 'HISTOPATHOLOGICAL CHANGES IN HEART AND LUNG OF ALBINO RAT TREATED WITH MACHETE HERBICIDE', Journal of Plant Protection and Pathology, 27(10), pp. 7043-7052. doi: 10.21608/jppp.2002.255354
Khidr, F. HISTOPATHOLOGICAL CHANGES IN HEART AND LUNG OF ALBINO RAT TREATED WITH MACHETE HERBICIDE. Journal of Plant Protection and Pathology, 2002; 27(10): 7043-7052. doi: 10.21608/jppp.2002.255354

HISTOPATHOLOGICAL CHANGES IN HEART AND LUNG OF ALBINO RAT TREATED WITH MACHETE HERBICIDE

Article 6, Volume 27, Issue 10, October 2002, Page 7043-7052  XML PDF (2.88 MB)
Document Type: Original Article
DOI: 10.21608/jppp.2002.255354
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Author
Fatma K. Khidr
Plant Protection Res. Institute, Agric. Res. Center, Dokki-Giza, Egypt
Abstract
The present study aims to illustrate the histopathological effect of 1/4 LD50
oral administration of herbicide Machete on heart and lung of albino rats at intervals
1, 2, 3, 4 and 5 weeks post-treatment. Significant decrease in body weight were
recorded, while a significant increase were recorded in heart and lung weight
comparing with control. Also, significant decrease in the number of erythrocytes,
leucocytes, haemoglobin level, haematocrit value and packed cell volume were
observed. Concerning the histopathological changes in heart, there was oedema,
inflammatory cells infiltration in the subendocardial tissue and the myocardial blood
vessels were hyperemic, while changes in lung, there was lymphoid cells aggregation
with hyperemic blood vessels in association with the presence of alveolar
emphysema in diffuse manner. Perivascular lymphoid cells aggregation and
peribronchiolar lymphoid hyperplasia were observed.
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