EI-Mahrouky,, F., Khidr, F., Abdel-Aal, S., Zedan, H. (2003). HISTOLOGICAL EFFECTS OF HERBICIDE (MACHETE) 0 THE KIDNEY OF ALBINO RAT. Journal of Plant Protection and Pathology, 28(6), 5043-5051. doi: 10.21608/jppp.2003.244697
Fatma S. EI-Mahrouky,; Fatma K. Khidr; S. M. Abdel-Aal; H. A. Zedan. "HISTOLOGICAL EFFECTS OF HERBICIDE (MACHETE) 0 THE KIDNEY OF ALBINO RAT". Journal of Plant Protection and Pathology, 28, 6, 2003, 5043-5051. doi: 10.21608/jppp.2003.244697
EI-Mahrouky,, F., Khidr, F., Abdel-Aal, S., Zedan, H. (2003). 'HISTOLOGICAL EFFECTS OF HERBICIDE (MACHETE) 0 THE KIDNEY OF ALBINO RAT', Journal of Plant Protection and Pathology, 28(6), pp. 5043-5051. doi: 10.21608/jppp.2003.244697
EI-Mahrouky,, F., Khidr, F., Abdel-Aal, S., Zedan, H. HISTOLOGICAL EFFECTS OF HERBICIDE (MACHETE) 0 THE KIDNEY OF ALBINO RAT. Journal of Plant Protection and Pathology, 2003; 28(6): 5043-5051. doi: 10.21608/jppp.2003.244697
HISTOLOGICAL EFFECTS OF HERBICIDE (MACHETE) 0 THE KIDNEY OF ALBINO RAT
1Plant Protection Research Institute, ARC, Dokkl-Glza .
2Faculty of Agrtc., AL - Azhar Univ., Asslut., Egypt.
Abstract
The histological changes and some parameters in the kidney of albino rat re examined to show the effect of daily 1/4 lD50 (500 mg/kg b.w,) of herbicide Mac~~te afttir 151. 2.J)d, 3!d and 4th weeks post Ireatment. The results indicated a marlted SignifICant decrease in body weight, while a significant increase in kidney weight.
Kidney ; Hyperaemia was observed in the cortical blood vessels, while he epithelial cells lining the renal tubules had degenerative changes. Focal mononucl~ar leucocytic Inflammatory caUs infiltration was noticed inbetween the renal tubulel. It could be stated that Machete herbicide causes pathogenesis In kidney tissue I at
could possiblY leads to renal dysfunction. .
Also, total protein, total bilirubin, uric acid creatinine and urea were change in plasma of albino rat after oral administration 1/4 L050 herticlde Machete daily, it was
observed an increase in total bilirubin, uric acid, c:teatinine and urea but a gradually decreases was recorded in total protein level at an tested periods, except at1stwe k creatinine did not changed compared with control.
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